Structural FormulaO || HO-C-C / \ N C / \ C C || || O O
Molecular Weight115.09 Grams (g)
PropertiesPhysical Form Crystalline solid
Product Type Organic Intermediate
CAS No 6066-82-6
Molecular Formula C H NO
Molecular Weight 115.09 g/mol
EINECS No 228-001-3
HS Code 2921.19.00
Grade 98% (high purity)
Purity 98%
Appearance White to off-white crystalline powder
Shape Crystalline
Taste Not specified
Smell Odorless
Poisonous Yes, classified as harmful and hygroscopic
Used as a reagent in peptide synthesis to activate carboxylic acids for amide bond formation.
Involved in the preparation of NHS esters for protein labeling and modification.
Utilized in the carbodiimide method for improved amidations and peptide couplings.
Applied in biosensor development for enzyme immobilization
Other
228-001-3
Organic Intermediate
White to off-white crystalline powder
Pharma
Crystal
Pharmaceutical
Soluble in water, methanol, dimethylformamide, alcohols, and ethyl acetate; insoluble in cold ether
Other
93-100 C
O || HO-C-C / \ N C / \ C C || || O O
3 Years
29211900
115.09 Grams (g)
Physical Form Crystalline solid
Product Type Organic Intermediate
CAS No 6066-82-6
Molecular Formula C H NO
Molecular Weight 115.09 g/mol
EINECS No 228-001-3
HS Code 2921.19.00
Grade 98% (high purity)
Purity 98%
Appearance White to off-white crystalline powder
Shape Crystalline
Taste Not specified
Smell Odorless
Poisonous Yes, classified as harmful and hygroscopic
Powder Solid
6066-82-6
N Hydroxysuccinimide Trade Information
Hajira
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25000 Kilograms Per Month
3 Days
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Physical Form Crystalline solid
Product Type Organic Intermediate
CAS No 6066-82-6
Molecular Formula C H NO
Molecular Weight 115.09 g/mol
EINECS No 228-001-3
HS Code 2921.19.00
Grade 98% (high purity)
Purity 98%
Appearance White to off-white crystalline powder
Shape Crystalline
Taste Not specified
Smell Odorless
Poisonous Yes, classified as harmful and hygroscopic
Product Description
Peptide Synthesis:NHS is widely used in peptide synthesis to activate carboxylic acids for coupling reactions.It reacts with carboxylic acids in the presence of coupling reagents (like DCC or EDC) to form N-hydroxysuccinimide esters, which are highly reactive intermediates.These esters readily react with amines to form amide bonds, the backbone of peptides.
Bioconjugation: NHS esters are also used to conjugate proteins, peptides, and other biomolecules to various carriers, such as:
Fluorescent dyes: For labeling and tracking biomolecules.
Enzymes: For immobilization and biocatalysis.
Polymers: For creating biomaterials and drug delivery systems.
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